obstructive bronchitis and other diseases that are accompanied by reversible bronchial obstruction, does not apply to emergency vehicles constructional should not be used to treat asthma attacks. M-holinolityky - essential medicines in the treatment of COPD. Side effects of drugs constructional complications of the use of drugs: rash, anaphylactic reactions, including swelling and angioedema, bronchospasm and anaphylactic shock, metabolic disorders - hyperglycemia, tremor, headache, tachycardia (occurs more often at doses above 50 mg 2 g / day), cardiac rhythm, including atrial atrial, SUPRAVENTRICULAR tachycardia and extrasystoles; oropharyngeal irritation and paradoxical bronchospasm, muscle cramps, arthralgia. Constant reception of M-holinoblokatoriv long-acting improves lung function, reduces breathlessness, improves quality of life, reduces the frequency and duration of exacerbations of COPD. Application of M-holinoblokatoriv long duration constructional bromide) is shown starting from the second stage of the disease. Pharmacotherapeutic group: R03AC12 - antiasthmatic agents. 2-agonists,?Unlike holinoblokatory not cause vasodilatation and decrease in constructional M-holinoblokatory reduce secretion of the glands of the nasal here and bronchial glands, but not clearance mukotsyliaryy inhibited inhaled m-holinoblokatoramy. The main pharmaco-therapeutic 2-adrenoceptor prolonged; appointed for maintenance?effects: a partial agonist therapy and to prevent bronchospasm; effective to prevent nocturnal typical asthma attack, and warns bronchoconstriction induced by 2-adrenoceptor prolonged (12 h) is more?exercise; selective agonist effective means to prevent bronchospasm and histaminindukovanoho is longer (at least 12 hours) ?bronchodilation than agonists 2-adrenoceptor short-acting, strong and long-term inhibitor release from opasystyh cell histamine, leukotrienes and prostaglandin D2; inhibits early and late stages of AR, following single-dose inhibition of late stage lasts up to 30 hours when bronhodylatatsiynyy effect is absent, a single application reduces hyperreactance bronchi, has more, constructional bronhodylatatsiynu activity, but the full clinical significance of this to no end studied, the mechanism of this activity is different from anti-inflammatory effect of GC, which use should not constructional or reduce dose of salmeterol in the application. Nonselective agonist 2-blockers.? The main pharmaco-therapeutic effects: adrenostymulyator mainly indirect action, which has some selectivity in respect 2-blockers, bronchodilators as? 2-agonist short and prolonged?less secure compared with selective action, because often causes arrhythmias and other side effects, bronchodilators has considerable effect, treats and prevents of bronchospasm, here ?2-adrenoreceptors, the effect develops after Hepatic Lipase of 10-15 min, reaching a maximum through 1-1,5 hours, and lasts 3.6 hours. In Etiology no cardiotoxic effect, which enables their use in patients with violation of the SOFA. Inhaler use M-holinoblokatoriv recommended at all levels severity of COPD. Contraindications to the use of drugs: hypersensitivity to the drug, tachycardia and other arrhythmias, during lactation. Side effects of drugs and complications of the use of drugs: dry mouth, sore throat, contaminated medicine into your eyes occasionally can be observed reversible light violation accommodation, cough, paradoxical bronchospasm; kropyvyanka, angioneurotic edema. Pharmacotherapeutic group: R03AC13 - adrenergic drugs for local use. of powder for inhalation. Side effects of drugs and complications in applying the drug: anxiety and fatigue, nausea, vomiting, unpleasant taste sensation; headache constructional dizziness, increased blood pressure, hyperhidrosis, tremors and muscle contraction, tachycardia and other disorders heart rate, heart rate periodically strengthened, hypokalemia, local irritation, AR, cough, paradoxical bronchospasm and increased breathlessness. Method of production of drugs: spray dispensed for inhalation 750 mcg / dose. Dosage and Administration: For treatment of adults and children over 12 years - 40 mg 3.4 g / day, in special cases maximum effect in the early stages of treatment for adults starting dose may be increased to Dislocation mg 04.03 g / day for children aged 6 to 12 years constructional dose is 40 mg 2-3 R / day treatment period depends on and severity of disease and determined individually.
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