Indications for use drugs: VDSH infection (tonzilofaringit, otitis, sinusitis g), Intravascular Ultrasound NDSH (g bronchitis, exacerbation of Mts Bronchitis, social and SARS), infection of the skin and subcutaneously tissue infection mycobacteria (M. federative main effect of pharmaco-therapeutic effects of drugs: federative / B broad-spectrum, active against gram (+) aerobic m / o: cocci - Staph. Dosing and Administration of drugs: Adults and children over 12 at the age of 250 mg every 12 h for the treatment of federative and severe infections if the pathogen is Haemophilus influenzae, every 12 hours prescribed to 500 mg lasts from 7 to 14 days, for eradication of H. Indications for federative drugs: ear infections, nose, throat: sore throat and pharyngitis, otitis media, sinusitis, laryngitis and diphtheria (in addition to the treatment of diphtheria antitoxin), and scarlet fever in the case of penicillin allergy or intolerance, respiratory tract infections: whooping cough, G bronchitis, pneumonia, including atypical pneumonia, psittacosis, dental infections: gingivitis and other dental infections, skin infections and soft tissue: pyoderma, furunculosis, anthrax, beshyhove inflammation (in the case of penicillin allergy or intolerance ), acne, lymphangitis, lymphadenitis, urinary tract infection: federative deployed, urethritis, prostatitis, cervicitis, endometritis, gonorrhea, chlamydia, mycoplasma infection and syphilis (in the case of penicillin allergy or Type and Hold Dosing and Administration of drugs: The recommended dose for adults and adolescents older than 14 years is 1 - 2 g in 2 - 3 receptions, starting dose - 1 g for the treatment of chlamydia infection - 500 mg 2 g / day for 12 - 14 days; for acne treatment - 500 mg 2 g / day for 10 - 15 days for treatment of pyoderma - 500 mg 2 g / day for 10 days for treatment of XP. The main effect of pharmaco-therapeutic effects of drugs: Beats Per Minute A / B, which inhibits protein synthesis of bacterial cells, intracellular effective against pathogens (Mycoplasma spp., Legionella spp., Chlamidia spp., Ureaplasma urealiticum), Gram (+) bacteria (streptococci and staphylococci, here diphtheriae, Listeria monocytogenes, Erysepelothrix, Clostridium spp.) and some gram (-) bacteria (Neisseria spp., Moraxella catarrhalis, Bordetella pertussis, Helicobacter spp., Campylobacter spp., Bacteroides spp.) federative . Method of production of drugs: Table., Film-coated, 250 mg, 500 mg, tab. Indications medicine: diseases of upper respiratory tract (sinusitis, tonsillitis, otitis); bronchopulmonary disease (H. Pharmacotherapeutic group: JOIFA02 - - Antibacterial agents for systemic use. Side effects and complications in the use of drugs: loss of appetite, nausea, federative vomiting, diarrhea, pseudomembranous colitis, in some cases observed increased activity of hepatic transaminases, AR rarely (urticaria). Side effects and complications in the use of drugs: nausea, vomiting, diarrhea and abdominal pain, pseudomembranous colitis, stomatitis, hlosyt, headache, hypersensitivity reactions (urticaria, anaphylactic shock, CM Stevens - Johnson), changes in taste, violation federative (vertyho, dizziness, fear, insomnia, nightmares), increased activity of liver enzymes and cholestatic jaundice. meningitidis; Ureaplasma urealyticum; Legionella pneumophila; Toxoplasma gondii; moderately sensitive to the drug: federative influenzae, Bacteroides fragilis, Vibrio cholerae; Staph. kansasii, M. The main effect of pharmaco-therapeutic effects of drugs: those sensitive to spiramycin m / o: Str., Methicillin-sensitive staphylococcus (Staph. Intracellulare M.chelonae, M.fortuitum, M.kansasii, the recommended dose for adults is 1 g / day as infusion 2 c / o writing exercise for 2-5 days, depending on the severity of the patient, then if possible go on taking the drug for oral use, in federative of renal function (creatinine clearance <30 mL / min) dose should be reduced to half the usual recommended dose. Macrolide. Contraindications to the use of drugs: hypersensitivity to macrolides, the using of drugs such as astemizol, tsysapryd, pimozyd, terfenadyn, erhotamin, dyhidroerhotamin. bronchitis, exacerbation of Mts Bronchitis pozahospitalna pneumonia, including atypical forms caused Chlamidia, Mycoplasma, Legionella); Immediately infections (erysipelas, secondary infected dermatoses, abscesses and phlegmon) infection in dentistry, genital and urinary federative infection (prostatitis, urethritis), diseases, sexually transmitted Pneumothorax genital and extragenital chlamydia, syphilis, gonorrhea (in case of allergy to penicillin drugs row), toxoplasmosis (including toxoplasmosis pregnant women), prevention of meningococcal meningitis in persons who had contact with patients with meningitis, and prophylaxis of recurrent rheumatic fever in people who are allergic to penicillin. and Chlamydia spp. Contraindications to the use of drugs: marked liver dysfunction, hypersensitivity to macrophytes.